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PROJECT 00-57
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New Generation of Smart Polymers and Polymeric
Materials for Biotechnology
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September
1, 2001 – August 31, 2004
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Co-ordinator - Professor Bo Mattiasson
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The main goal of this Project is to develop a
new generation of “smart (intelligent)” polymers and polymeric materials
for the biotechnological implementation. New, not well so far known,
approaches will be used to fabricate smart polymers taking into account the
requirements implied by biotechnological use of these polymeric products.
The main objectives of the project are:
- to investigate
cryotropic gelation approach as the method to prepare supermacroporous
cryogels with thermo- and/or pH-sensitivity,
- to study the
influence of dispersed fillers on the morphology, rheological and
swelling characteristics of filled cryogels,
- to develop the
synthetic procedure for polyelectrolyte hydrogels with imbedded voids,
- to develop the
methodology of preparation of the temperature-sensitive hydrogels with
balanced hydrophilic/hydrophobic ratio, as well as of the hybrid
hydrogels,
- to investigate
thermophysical characteristics and physico-mechanical properties of
new gel materials with modern physical methods
The
compulsory important part of the Project is the examination of the
developed polymeric materials in the biotechnological areas (bioseparation,
immobilization, cell culture, drug delivery, etc.) and search for new
applications areas.
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 Six research teams (two from
INTAS members, three from Russia and one from Kazakhstan) with
complementary expertise will be involved in the project. Different
experimental techniques will be
used for synthesis and study of new smart polymer and polymeric materials.
The experimental studies will be supported by theoretical investigations.
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Professor
Bo Mattiasson
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Department of Biotechnology,
Center for Chemistry and Chemical Engineering,
Lund University,
Lund, SWEDEN
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Professor Pnina Vardi
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Laboratory
of Obesity and Diabetes Research,
Felsenstein
Medical Research Centre,
Tel-Aviv
University, ISRAEL
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Professor
Vladimir
Lozinsky
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Laboratory for
Cryochemistry of (Bio) Polymers,
Institute of
Organoelement Compounds of the Russian Academy of Sciences,
Moscow, RUSSIA
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Professor
Alexei
Khokhlov
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Chair of Polymer and
Crystal Physics,
Physics Department,
Moscow State University
Moscow, RUSSIA
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Professor
Valerii Grinberg
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Laboratory
for Protein Systems,
Institute
of Biochemical Physics
of
the Russian Academy of Sciences,
Moscow, RUSSIA
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Professor Sarkyt Kudaibergenov
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Institute of Polymer
Materials and Technology,
Alma-Ata, KAZAKHSTAN
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